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  • NCARD Research Fellowship

    December 2018

    Reflections is proud to support the important work being undertaken to improve diagnosis and treatment outcomes for mesothelioma and other asbestos-related diseases.

    In 2016 we had the opportunity to contribute $50,000 to fund a research fellow at the National Centre for Asbestos Related Diseases (NCARD), Dr Linda Ye. Dr Le has since completed her Research Fellowship in lung cancer research and is inspired to continue onto a PhD.

    Acknowledgement by Professor Anna Nowak, Director NCARD

    On behalf of the National Centre for Asbestos Related Diseases (NCARD), I wish to thank you for Reflections Through Reality’s generous research support. As you will read in this report, NCARD celebrated many achievements of staff and students in 2018.

    A key aspect of NCARD’s collaborative research future is recognising and developing exceptional, passionate and determined research students. Your support has seen Dr Linda Ye complete her Research Fellowship with us at NCARD in lung cancer research and inspired her to continue onto a PhD. Dr Ye represents the next generation of researchers who will build on our work and develop the breakthroughs of the future.

    Thank you once again for your ongoing support and investment in our vision.

    Clinical trial preparations

    During her lung cancer fellowship, under the primary supervision of Professor Bruce Robinson, Linda worked with the NCARD team to develop, write, and achieve ethics approval of a clinical trial protocol looking to explore the novel therapeutic strategy of neoantigen vaccination, initially in patients with lung cancer, with expansion into mesothelioma planned in the future. This treatment is expected to help one’s own immune system fight the cancer by generating an immune response against an individual’s unique cancer mutations. Ongoing planning and development are underway and the trial will be ready to start recruiting in the near future.

    Lung cancer research projects

    Additionally, Linda conducted regular lung cancer clinics and undertook two research projects based on molecular testing of lung cancer. These two projects helped to assess the pattern of expression of immunological and molecular markers in the Western Australian lung cancer population, and demonstrated the efficacy and feasibility of a new molecular test to detect a specific mutation seen in lung cancer. These projects were both presented at the Australasian Lung Cancer Conference in 2018, one has been accepted for publication and the other has just been submitted for publication.

    Future plans

    Linda enjoyed her time as the NCARD research fellow immensely and the opportunity provided her with invaluable research and clinical experience, made possible by Reflections Through Reality. She hopes to continue lung and mesothelioma related research in the future and is currently planning to pursue a PhD through the neoantigen vaccine project.

    Download the full report here